Moodle at CCNM

Organ reserve was first was described in the 80s by Dr. James Fries after seeing the significant variability in function in geriatric populations. Defined as innate and environmentally induced modes of favorable adaption that lead to extended cellular defense as well as physical and cognitive function, this construct is not just about genes. Environmental exposures such as diet and medicinal plants appear to play a significant role in extending functional capacity. Unfortunately, the paradigm of organ reserve is poorly understood in clinical therapeutics four decades later. We discuss this insightful and clinically relevant model and the implications of the trophorestorative plants that may preserve our reserve and induce the ability of organs to successfully return to their original physiological state following repeated episodes of biochemical, physical and emotional stress.

While much of the medical community is learning about the cannabinoids, the Cannabis industry itself has been enamored by the terpenes, specifically the mono and sesquiterpenes, with good reason. Many of the terpenes are known to be psychotropic, alter pharmacokinetics and potentially enhance the pharmacodynamic of the cannabinoids. The current understanding of chemovars, is arguably about terpene profiles rather than cannabinoid profiles, and these profiles offer a better understanding of indica vs. sativa differences than supposed speciation.